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Year : 2014  |  Volume : 20  |  Issue : 2  |  Page : 70-74

Dexmedetomidine and propofol for monitored anesthesia care in the middle ear surgery

1 Department of Anaesthesiology and Critical Care, King George's Medical University, Lucknow, Uttar Pradesh, India
2 Department of ENT and Head and Neck Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Rajni Gupta
Department of Anaesthesiology and Critical Care, King George's Medical University, Lucknow, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-7749.131872

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Context: Local anaesthesia with sedation is a well established approach used for tympanoplasty. Dexmedetomidine is a new drug which acts on α2-adrenergic receptors in the dorsal horn of the spinal cord to produce analgesic effects. Aims: Efficacy and safety of intravenous dexmedetomidine in comparison to propofol. Setting and Design: Randomized controlled trial. Materials and Methods: Eighty patients were randomly allocated to receive either dexmedetomidine or propofol as intravenous bolus followed by the same in infusion supplemented with local anaesthesia for tympanoplasty. Statistical Analyses Used: Statistical Package for Social Sciences version 15.0. Results: Dexmedetomidine and propofol provides adequate sedation but the use of propofol is associated with more requirements of rescue analgesia and poor patient and surgeon satisfaction. Conclusion: These results suggest that dexmedetomidine provides adequate sedation with analgesia and good surgical and patient comfort without any adverse effects for patients undergoing tympanoplasty under local anaesthesia

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